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目的通过对蓟县地区人间布氏菌病(布病)疫情的调查,查明病例感染途径、发病和诊治经过、经济负担情况等,为制定布病预防控制相关措施提供依据。方法通过描述性流行病学进行疫情分析、就诊情况和经济负担,通过病例对照研究布病的危险因素。结果 2004-2009年无布病病例报告、2010年和2011年分别报告1例、2012年报告4例;6例病例中只有1例病例在就诊前即知晓布病;布病花费平均费用12060元。病例发病前均有羊、犬等家畜长期接触史,接触羊流产物能增加发病风险(OR值15.0,95%CI1.2~185.2,P<0.05)。医疗机构对布病误诊率为66.67%(14/21)。结论天津市蓟县地区布病疫情有上升趋势,提高医务人员布病诊断知识和意识、加强对畜牧业养殖人员布病预防知识宣传是当务之急。
Objective To investigate the epidemic situation of human brucellosis (brucellosis) in Jixian area, and to identify the pathways of infection, incidence, diagnosis and treatment, economic burden and so on, so as to provide basis for formulating the measures for prevention and control of brucellosis. Methods Epidemiological analysis of epidemiology, treatment and financial burden, by case-control study of brucellosis risk factors. Results No case of brucellosis was reported in 2004-2009, 1 case was reported in 2010 and 2011 and 4 cases were reported in 2012. Only 1 case out of 6 cases was known to be diagnosed before treatment. The average cost of brucellosis was 12,060 yuan . Before the onset of the disease, sheep, dogs and other livestock had long-term exposure history. Exposure to sheep products increased the risk of onset (OR 15.0, 95% CI 1.2-285.2, P <0.05). The rate of misdiagnosis of brucellosis in medical institutions was 66.67% (14/21). Conclusion The epidemic situation of brucellosis in Jixian area of Tianjin is on the rise. It is imperative to improve the knowledge and awareness of medical personnel in the diagnosis of brucellosis and to strengthen knowledge of prevention of brucellosis among livestock husbandry personnel.