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目的了解湖北省人群免疫状况,评价预防接种质量和效果,制定免疫对策。方法分七个年龄组抽取黄石和咸宁两个地区部分健康人群,采用ELISA法定量检测正常人血清中百日咳、白喉和破伤风IgG抗体水平。结果两个地区健康人群中,百日咳IgG抗体阳性率为27.14%,白喉和破伤风IgG抗体安全保护率分别为55.71%和60.29%。结论抽取的湖北省两个地区健康人群百日咳、白喉和破伤风IgG抗体阳性率均比较低,提示要扩大接种覆盖率,缩短强化免疫周期,提高冷链运转效率和疫苗接种质量。
Objective To understand the population immunization status in Hubei Province, evaluate the quality and effectiveness of vaccination and formulate immunization strategies. Methods Seventy age groups were selected from the healthy population in two districts of Huangshi and Xianning. The levels of pertussis, diphtheria and tetanus IgG antibodies in serum were quantified by ELISA. Results The positive rates of pertussis IgG antibody in the two regions were 27.14%, and the safety protection rates of diphtheria and tetanus IgG antibodies were 55.71% and 60.29% respectively. Conclusions The positive rates of pertussis, diphtheria and tetanus IgG antibodies in healthy population from two regions of Hubei Province are relatively low, suggesting that it is necessary to expand vaccination coverage, shorten the duration of intensive immunization and improve cold chain operation efficiency and vaccination quality.