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近年来,他汀类药物用于防治心血管疾病的临床研究成果显著,为该类药物在血脂相关性疾病治疗中奠定了地位。其次,他汀类药物对抗血栓、改善内皮功能等较多方面均有良好效果。故随着血脂相关性疾病患病率不断增高,他汀类药物的临床应用也日益广泛,中国血脂异常调查研究(DYSIS-China)结果显示[1],在中国近九成的血脂异常患者在接受他汀类药物治疗,但由于任何药物有其药物不良反应,大剂量用药患者
In recent years, statins for the prevention and treatment of cardiovascular disease clinically significant results for the class of drugs in the treatment of blood-lipid-related diseases has laid the status. Second, statins have good effects against many aspects of thrombosis and endothelial function. Therefore, with the increasing prevalence of blood-lipid-related diseases, the clinical application of statins is also increasingly widespread. The results of the DYSIS-China survey [1] show that nearly 90% of dyslipidemia patients in China are receiving Statin therapy, but because of any drug has its adverse drug reactions, high-dose patients