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目的:分析甲氨蝶呤联合米非司酮治疗异位妊娠的临床效果及安全性。方法:研究对象为2016年2月~2017年2月我院收治的且被确诊为患有异位妊娠的102例患者。采用随机法将两组患者分为对照组与观察组,各51例,给予对照组与观察组患者分别采用甲氨蝶呤与甲氨蝶呤联合米非司酮进行治疗,对比分析两组患者的治疗效果及安全性。结果:对照组与观察组患者的总有效率分别为94.12%与78.43%,不良反应发生率分别为11.77%%与1.96%对照组的总有效率明显低于观察组,且不良反应发生率高于观察组,差异具有统计学意义(P<0.05)。结论:采用甲氨蝶呤联合米非司酮治疗异位妊娠的临床疗效更佳,更具安全性。
Objective: To analyze the clinical effect and safety of methotrexate combined with mifepristone in the treatment of ectopic pregnancy. Methods: The study included 102 patients admitted to our hospital from February 2016 to February 2017 and who were diagnosed with ectopic pregnancy. Randomly divided the two groups into control group and observation group, 51 cases in each group. The patients in control group and observation group were treated with methotrexate and methotrexate combined with mifepristone respectively. Therapeutic effect and safety. Results: The total effective rates of the control group and the observation group were 94.12% and 78.43% respectively, the rates of adverse reactions were 11.77 %% and 1.96%, respectively. The total effective rate of the control group was significantly lower than that of the observation group and the incidence of adverse reactions was high In the observation group, the difference was statistically significant (P <0.05). Conclusion: Methotrexate combined with mifepristone in the treatment of ectopic pregnancy has better clinical efficacy and more safety.