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[目的]观察半夏泻心汤联合西药治疗慢性萎缩性胃炎疗效。[方法]使用随机平行对照方法,将100例住院患者按就诊顺序号法简单随机分为两组。对照组50例维酶素,0.8g/次,3次/d,饭前30min口服;胃复春,1.44g/次,3次/d,饭前30min口服。治疗组50例半夏泻心汤(黄连6g,大枣4颗,黄芪、半夏各15g,党参2g,三七粉分冲2g,乌贼骨、玄胡、白花蛇舌草各3g,丹参2g,三棱15g,甘草6g;痞满加枳实、砂仁;纳差加木香、鸡内金、砂仁;胃脾痛加白芍;大便干燥、数天不排便加决明子、麻仁;幽门螺旋杆菌阴性加蒲公英、鱼腥草;舌苔厚腻加白术、苍术、薏苡仁),1剂/d,水煎300m L,早晚服用;西药治疗同对照组。连续治疗90d为1疗程。观测临床症状、胃膜色泽、胃腺体萎缩、颗粒状增生、不良反应。治疗1疗程,判定疗效。[结果]临床疗效:治疗组显效13例,有效27例,无效10例,恶化0例,总有效率100.00%。对照组显效4例,有效15例,无效21例,恶化10例,总有效率38.88%。病理疗效:治疗组显效15例,有效30例,无效5例,恶化0例,总有效率90.00%。对照组显效8例,有效16例,无效16例,恶化10例,总有效率48.00%。治疗组疗效优于对照组(P<0.01)。[结论]半夏泻心汤联合西药治疗慢性萎缩性胃炎效果显著,无严重不良反应,值得推广。
[Objective] To observe the curative effect of Banxiaxiexin Decoction combined with western medicine on chronic atrophic gastritis. [Methods] Using randomized parallel control method, 100 cases of inpatients were randomly divided into two groups according to the sequence number of attendance. The control group of 50 patients with ubiquitin, 0.8g / time, 3 times / d, 30min before meals orally; Weifuchun, 1.44g / time, 3 times / d, 30min before meals orally. The treatment group of 50 cases of Banxiaxiexin soup (Coptis 6g, jujube 4, Astragalus, Pinellia each 15g, Codonopsis 2g, notoginseng Fen 2g, cuttlefish bone, Xuanhu, Hedyotis diffusa each 3g, Salvia 2g , Prismatic 15g, licorice 6g; Prickly heat plus Fructus Aurantii, Amomum villosum; Anadromycin woody, Chickens gold, Amomum villosum; stomach spleen pain and white peony root; dry stool, Helicobacter pylori negative plus dandelion, Houttuynia; thick tongue and greasy plus Atractylodes, herb, Yiyiren), 1 / d, decoction 300m L, taken sooner or later; Western medicine treatment with the control group. Continuous treatment of 90d for a course of treatment. Observation of clinical symptoms, stomach color, gastric gland atrophy, granular proliferation, adverse reactions. Treatment of a course of treatment to determine the efficacy. [Results] Clinical curative effect: The treatment group was markedly effective in 13 cases, effective in 27 cases, ineffective in 10 cases, worsening in 0 cases, the total effective rate was 100.00%. In the control group, 4 cases were markedly effective, 15 cases were effective, 21 cases were ineffective and 10 cases were deteriorated. The total effective rate was 38.88%. Pathological effects: The treatment group markedly effective in 15 cases, effective in 30 cases, 5 cases of ineffective, 0 cases of deterioration, the total efficiency of 90.00%. The control group was markedly effective in 8 cases, effective in 16 cases, ineffective in 16 cases, worsening in 10 cases, the total effective rate was 48.00%. The treatment group than the control group (P <0.01). [Conclusion] Banxiaxiexin Decoction combined with western medicine has significant effect on chronic atrophic gastritis, without serious adverse reactions, which is worth popularizing.