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目的:研究喜炎平联合干扰素治疗手足口病的临床效果。方法:选取东莞市桥头医院2015年6月至2016年8月所收治的66例手足口病患儿作为本次研究对象,按照就诊时间将其分为观察组和对照组,每组各33例,对照组应用喜炎平治疗,观察组在此基础上加用干扰素治疗,对比分析两组患儿的治疗效果、平均退热天数与皮疹消退天数,并观察两组患者的口腔疱疹消失时间、疼痛消退时间。结果:观察组治疗总有效率(93.94%)显著高于对照组(72.73%),观察组平均退热天数(1.87±1.35)d与皮疹消退天数(3.61±1.56)d明显少于对照组(3.21±1.67)d、(5.99±2.41)d,观察组口腔疱疹消失时间(2.87±0.6)d、(2.87±0.59)d与疼痛消退时间显著短于对照组(3.98±0.64)d、(4.87±0.72)d,两组差异明显,差异具有统计学意义(P<0.05)。结论:喜炎平联合干扰素治疗手足口病的临床疗效显著,能够有效缩短退热天数和皮疹消退天数。
Objective: To study the clinical effect of Xiyanping combined with interferon in the treatment of hand, foot and mouth disease. Methods: Sixty-six children with hand-foot-mouth disease admitted from June 2015 to August 2016 in Qiaotou Hospital of Dongguan City were enrolled in this study. According to the time of treatment, they were divided into observation group and control group, with 33 cases in each group , The control group was treated with Xiyanping, the observation group was treated with interferon on the basis of this study. The therapeutic effect, the average number of days of fever relief and the days of rash subsided were compared between the two groups. Oral herpes disappearance time , Pain subsided time. Results: The total effective rate (93.94%) in the observation group was significantly higher than that in the control group (72.73%), and the mean days of fever relief in the observation group (1.87 ± 1.35 days) and the days of rash subsided (3.61 ± 1.56) days were significantly lower than those in the control group (2.87 ± 0.6) d and (2.87 ± 0.59) d, respectively, and pain relief time in the observation group was significantly shorter than that in the control group (3.98 ± 0.64, ± 0.72) d, significant difference between the two groups, the difference was statistically significant (P <0.05). Conclusion: The clinical efficacy of Xiyanping combined with interferon in the treatment of HFMD is significant, which can effectively shorten the days of fever and days of rash subside.