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为了解儿童感染性心内膜炎（ＩＥ）的变迁，将１９８４～１９９７年我院确诊的ＩＥ３２例与１９６４～１９８３年的ＩＥ３４例进行比较。结果显示：近１４年风心病作为引起ＩＥ的基础疾病的比例下降（从２６．５％降至１２．５％降至１２．５％），而无基础心脏病者明显增加（从１４．７％升至７８．１％）。致病菌中金黄色葡萄球菌明显减少，而条件致病菌明显增加（ Ｐ ＜０． ０５）。临床表现淤点（斑）、脾肿在、动脉栓塞有所下降，而心力衰竭明显增加（ Ｐ＜０． ０５）。结合超声心动图（ＵＣＧ）检查，讨论左右心内膜炎的临床特点，提出心力衰竭及栓塞是ＩＥ的主要致死病因，强调ＵＣＧ在诊断ＩＥ中的重要价值和适当治疗的重要性。
To understand the changes of children with infective endocarditis (IE), 1984 to 1997 in our hospital confirmed IE32 cases and 1964 ~ 1983 IE34 cases were compared. The results showed that in the past 14 years, the proportion of rheumatic heart disease as the underlying cause of IE decreased (from 26.5% to 12.5% to 12.5%), while those without underlying heart disease increased significantly (from 14.7 % To 78.1%). Pathogens Staphylococcus aureus significantly reduced, while the conditions of pathogens was significantly increased (P <0. 05). Clinical manifestations of petechia (spot), splenomegaly, arterial embolization decreased, while significantly increased heart failure (P <0. 05). Combined with echocardiography (UCG) examination to discuss the clinical features of left and right endocarditis, proposed that heart failure and embolism are the major cause of death in IE, emphasizing the importance of UCG in the diagnosis of IE and the importance of proper treatment.