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目的:观察去氧孕烯炔雌醇片治疗药物流产后阴道持续出血的临床疗效和安全性。方法:将98例药物流产后阴道出血达2周及以上,彩超除外宫内残留的患者,随机分为观察组(49例)和对照组(49例),观察组服用去氧孕烯炔雌醇片治疗;对照组服用五加生化胶囊治疗,观察两组患者的疗效和安全性。结果:观察组和对照组的成功止血率分别为91.84%和63.27%,治疗后月经复潮率分别为83.67%和34.69%,经量少于或等于既往月经量的比例分别为83.67%和32.65%,两组间差异均具有统计学意义(P<0.05或0.01)。观察组2例出现轻微恶心,能耐受,未终止用药,对照组无不良反应发生。结论:去氧孕烯炔雌醇片治疗药物流产后持续阴道出血的疗效较好,不良反应较少。
Objective: To observe the clinical efficacy and safety of DEEG ethinyl estradiol tablets in the treatment of persistent vaginal bleeding after medical abortion. Methods: 98 cases of vaginal bleeding after drug abortion for 2 weeks and above, except for the intrauterine residual ultrasound color Doppler ultrasound were randomly divided into observation group (49 cases) and control group (49 cases), the observation group taking desoxygluterine ethin Alcohol tablets treatment; control group taking five plus biochemical capsules treatment, the two groups observed the efficacy and safety. Results: The successful hemostasis rates of the observation group and the control group were 91.84% and 63.27%, respectively. After treatment, the rates of menstrual crassness were 83.67% and 34.69% respectively. The proportion of menstruation less than or equal to the previous menstrual flow was 83.67% and 32.65 %, The differences between the two groups were statistically significant (P <0.05 or 0.01). The observation group 2 patients showed mild nausea, can tolerate, did not stop the medication, the control group no adverse reactions. Conclusion: The effect of sustained-release vaginal bleeding is better and the adverse reaction is less after the treatment of abortion ethinyl estradiol tablets.