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过去10年,心肌细胞的再生疗法治疗缺血性心脏病的研究取得了长足进步。早期临床试验已证明细胞疗法的安全性。随着干细胞研究的深入,新型干细胞不断被研发,干细胞治疗领域不断扩展。诱导多能性干细胞的研发鼓舞了科学家应用干细胞治疗疾病的热情。尽管目前的研究还有许多有待于解决的问题和困难,细胞治疗心脏疾病可能会成为未来方向的主流。文章综述了有关新的干细胞研发及最新进展情况。
Over the past 10 years, the regenerative therapy of cardiomyocytes has made great strides in the research of ischemic heart disease. Early clinical trials have demonstrated the safety of cell therapy. With the deepening of stem cell research, new types of stem cells have been continuously developed and the field of stem cell therapy has been expanding. The development of induced pluripotent stem cells has inspired the enthusiasm of scientists to apply stem cells to treat diseases. Although there are still many problems and difficulties to be solved in current research, cell-based treatment of heart disease may become the mainstream in the future. The article summarizes the new stem cell research and development and the latest developments.