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目的研究雌激素对提高宫颈鳞柱交界带在阴道镜下的可见性的作用。方法对60例宫颈TCT或巴氏涂片显示非正常细胞,并且鳞柱交界带在阴道镜检查中不能暴露者予以小剂量雌、孕激素、安慰剂口服10日后复查阴道镜。通过实验数据对雌孕激素对鳞柱交界带的影响进行分析。结果雌激素组在阴道镜下鳞柱交界带可见率明显高于安慰剂组(70%相对于25%),此组进行锥切术的比例明显减少(P<0.01),而孕激素组与安慰剂组无明显区别,交界带可见率甚至小于对照组。结论雌激素可以提高宫颈鳞柱交界带在阴道镜下的可见性,从而避免不必要的宫颈锥切术。
Objective To study the effect of estrogen on improving the visibility of cervical squamous junction under colposcopy. Methods 60 cases of cervical TCT or Pap smear showed abnormal cells, and the squamous junction zone colposcopy can not be exposed to small doses of estrogen and progesterone, placebo orally 10 days after the review colposcopy. The effects of estrogen and progesterone on the junction of scale and column were analyzed by experimental data. Results The rate of visible esophageal squamous junction in the estrogen group was significantly higher than that in the placebo group (70% vs. 25%). The proportion of conization in this group was significantly decreased (P <0.01) No significant difference between the placebo group, the junction with the visible rate is even less than the control group. Conclusion Estrogen can improve the visibility of the cervical squamous junction under colposcopy, so as to avoid unnecessary cervical conization.