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目的探讨雌孕激素序贯疗法对稽留流产刮宫术后患者的应用效果。方法 80例稽留流产刮宫术后患者,根据治疗方法的不同分为对照组(38例)和观察组(42例)。对照组患者采用常规抗感染治疗,观察组患者采用常规抗感染联合雌孕激素序贯治疗。比较两组患者阴道出血时间、治疗后子宫内膜厚度及月经复潮时间、宫腔粘连发生情况。结果两组患者阴道出血时间比较差异无统计学意义(P>0.05);观察组患者月经复潮时间显著短于对照组,治疗后子宫内膜厚度厚于对照组,差异均具有统计学意义(P<0.05)。观察组宫腔粘连发生率为4.76%,高于对照组的21.05%,差异具有统计学意义(P<0.05)。结论对于稽留流产刮宫术后患者,在常规抗感染的基础上加以雌孕激素序贯疗法治疗疗效确切,值得临床进一步推广。
Objective To investigate the effect of sequential therapy of estrogen and progesterone on patients after missed abortion. Methods Eighty patients with missed abortion after curettage were divided into control group (38 cases) and observation group (42 cases) according to the different treatment methods. Control group of patients with conventional anti-infective treatment, observation group patients with conventional anti-infective combined with progesterone sequential treatment. The vaginal bleeding time, the thickness of endometrium after treatment, the time of menstrual resuscitation and the intrauterine adhesions were compared between the two groups. Results There was no significant difference in the time of vaginal bleeding between the two groups (P> 0.05). The duration of menstruation was significantly shorter in the observation group than in the control group. The thickness of the endometrium in the observation group was thicker than that in the control group (P> 0.05) P <0.05). The incidence of intrauterine adhesions in the observation group was 4.76%, which was higher than that in the control group (21.05%), the difference was statistically significant (P <0.05). Conclusion For patients with missed abortion after curettage, estrogen and progesterone sequential therapy on the basis of routine anti-infective treatment is effective and worthy of further clinical promotion.