动脉粥样硬化是心血管系统疾病的重要病理改变。目前,已发现多种糖基化磷脂酰肌醇锚定蛋白与动脉粥样硬化的发生、发展密切相关。CD14参与了动脉粥样硬化的慢性炎症过程;T-钙黏着蛋白可作为LDL的受体与动脉粥样硬化联系密切;其他的糖基化磷脂酰肌醇锚定蛋白如CD87等参与了动脉粥样硬化时细胞的移行、粘附、凋亡和增殖等。 Atherosclerosis is an important pathological change in cardiovascular diseases. At present, it has been found that a variety of glycosylated phosphatidylinositol-anchored proteins are closely related to the occurrence and development of atherosclerosis. CD14 participates in the process of chronic inflammation of atherosclerosis; T-cadherin can serve as a receptor for LDL and is closely related to atherosclerosis; other glycosylated phosphatidylinositol-anchored proteins such as CD87 are involved in atherosclerosis Like cell migration, adhesion, apoptosis and proliferation.