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目的观察干扰素-α联合窄谱中波紫外线治疗皮肤T细胞淋巴瘤的临床疗效。方法我院2012年1月至2013年12月期间所收治的皮肤T细胞淋巴瘤患者中选取20例作为此次研究对象,随机分为观察组和对照组,两组患者的年龄、性别等一般情况比较没有明显的差异,有可比性,P>0.05,具有统计学意义。结果观察组患者的治疗有效率为90.0%,对照组患者的治疗有效率为60.0%,观察组患者治疗有效率明显高于对照组患者,P<0.05,差异具有统计学意义。结论对于皮肤T细胞淋巴瘤患者,采用干扰素-α联合窄谱中波紫外线治疗,有助于提高患者治疗总有效率,安全性较高,具有一定的应用价值和治疗优势,值得大力推广使用。
Objective To observe the clinical efficacy of interferon-α combined with narrow-band UVB in the treatment of cutaneous T-cell lymphoma. Methods Twenty patients with cutaneous T-cell lymphoma who were treated in our hospital from January 2012 to December 2013 were selected as the study subjects and randomly divided into observation group and control group. The age and gender of the two groups were generally equal No significant differences in the situation, comparable, P> 0.05, with statistical significance. Results The effective rate of treatment was 90.0% in the observation group and 60.0% in the control group. The treatment efficiency in the observation group was significantly higher than that in the control group (P <0.05). The difference was statistically significant. Conclusions For patients with cutaneous T-cell lymphoma, the combination of interferon-α and narrow-band UVB will help to improve the total effective rate and safety of patients, which has certain value in application and treatment, and is worth promoting .