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喹哌是我国目前防治抗氯喹恶性疟的主要药物,1979年开始,在海南抗氯喹恶性疟流行区,广泛用于治疗和预防恶性疟疾,1982年以来,各地相继出现抗喹哌的恶性疟疾,而且日趋严重,给全岛抗疟带来新的困难。因此,查清抗喹哌恶性疟的地区分布和寻找治疗抗性虫株的替代药物,是海南当前疟疾防治工作急待解决的问题。现将近年来我们和省内外同道,在这方面的调查研究资料加以归纳,供进一步开展抗性的防治参考。
Quipiper is currently the main drug for the prevention and treatment of chloroquine-resistant falciparum malaria in our country. Since 1979, it has been widely used in the treatment and prevention of falciparum malaria in the anti-chloroquine-resistant malaria endemic area of Hainan. Since 1982, But it is becoming increasingly serious, bringing new difficulties to the entire island against malaria. Therefore, to find out the distribution of anti-Quipina falciparum malaria and to find alternative medicine for the treatment of resistant strains is the urgent problem to be solved in Hainan’s current malaria control. Now in recent years, we and other provinces and outsiders, in this regard, research data to be summarized for further prevention and treatment of resistance reference.