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人体自然杀伤细胞(Natural Killer Ceils)简称NK细胞,具有参与免疫病理损伤的潜在能力,并有广泛的免疫调节作用。儿童肾脏疾病发病机理中很多与免疫异常有关,本文检测32例儿童肾脏疾病的NK细胞活性,并对其临床意义作初步探讨。 资料和结果 一、对象 对32例儿童肾脏疾病急性期进行NK细胞活性检测,其原发疾病为单纯性肾病11例,肾炎性肾病3例,狼疮性肾炎2例,链球菌感染后急性肾炎5例,病毒性肾炎8例,尿路感染2例和肾挫伤1例。男21例,女11例;年龄4～11岁。2例单纯性肾病综合征检测时已接受激素治疗3～7天。
Natural Killer Ceils NK cells for short, have the potential to participate in immunopathological damage, and a wide range of immunomodulatory effects. Many of the pathogenesis of kidney disease in children are related to immune abnormalities. In this paper, NK cell activity of 32 children with kidney disease was examined, and its clinical significance was discussed. DATA AND RESULTS 1. Subjects NK cell activity was measured in 32 children with acute renal disease. The primary diseases were simple nephropathy in 11 cases, nephritic nephropathy in 3 cases, lupus nephritis in 2 cases, streptococcal acute nephritis 5 For example, 8 cases of viral nephritis, urinary tract infection in 2 cases and kidney contusion in 1 case. 21 males and 11 females; aged 4 to 11 years old. 2 cases of simple nephrotic syndrome test has been hormone therapy for 3 to 7 days.