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目的分析内蒙古地区乙脑减毒活疫苗的疑似预防接种异常反应(AEFI)发生特征。方法对内蒙古2009-2013年乙脑减毒活疫苗接种后发生并报告的疑似预防接种异常反应进行调查分析。结果全自治区报告疑似预防接种异常反应242例,报告发生率12.79/10万,一般反应223例,异常反应占19例,无后遗症和严重不良反应报告。全年5-7月和10-11月是报告高峰期,接种疫苗后24 h内监测到AEFI病例197例。结论内蒙古使用乙脑减毒活疫苗安全性较好。
Objective To analyze the characteristics of suspected immunization inoculation (AEFI) of live attenuated JE vaccine in Inner Mongolia. Methods The investigation and analysis on the abnormal reaction of suspected vaccination occurred and reported after the live attenuated JE vaccine in Inner Mongolia during 2009-2013 were conducted. Results 242 cases of suspected abnormal immunization were reported in the Autonomous Region, with a reported incidence of 12.79 / 100 000, 223 cases of general reaction, 19 cases of abnormal reaction, and no sequelae and serious adverse reactions. The annual reporting period from May to July and from October to November of the year was the peak period of reporting, and 197 cases of AEFI were detected within 24 hours after vaccination. Conclusion The safety of using live attenuated JE vaccine in Inner Mongolia is good.