本文报告小儿急性白血病生存１０年以上２８例，其中１２例生存１５年以上，最长者达１９年。２８例皆达白血病治愈。其中小儿急性淋巴细胞白血病２４例，急性非淋巴细胞白血病４例。并指出白血病细胞形态和临床分型，白血病细胞髓外浸润程度；白血病的早期诊断，诱导缓解，巩固强化、维持治疗、中枢神经系统白血病的预防以及强化疗方案皆为儿童急性白血病长期生存的重要因素。另外报导２例复发后经再次强化疗复治也得以长期生存１０年以上。 This article reports the survival of children with acute leukemia in more than 10 cases in 28 cases, of which 12 patients survived for more than 15 years, the longest up to 19 years. 28 cases of leukemia are cured. Including 24 cases of pediatric acute lymphoblastic leukemia, acute non-lymphocytic leukemia in 4 cases. And pointed out the leukemia cell morphology and clinical classification, leukemia cells extramedullary infiltration; early diagnosis of leukemia, induced remission, consolidation and consolidation, maintenance treatment, prevention of central nervous system leukemia and intensive chemotherapy are important for the long-term survival of children with acute leukemia factor. In addition, 2 cases were reported to have long-term survival of more than 10 years after re-intensive chemotherapy and re-treatment.