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目的观察氟哌噻吨美利曲辛对于胃溃疡伴抑郁症患者的临床治疗效果。方法将100例胃溃疡伴抑郁症患者随机分为观察组和对照组各50例。对照组给予常规药物治疗,观察组在对照组治疗基础上,加用氟哌噻吨美利曲辛进行治疗。观察记录2组患者治疗后的抑郁自评量表(SDS)评分和胃溃疡情况,并进行比较。结果观察组的胃溃疡治疗总有效率为96.0%显著高于对照组的82.0%(P<0.05)。治疗后,2组的SDS评分较之治疗前均出现不同程度的下降,但观察组SDS评分降低幅度显著大于对照组,差异均有统计学意义(P<0.05)。2组患者均未出现肝肾功能等异常现象,2组不良反应发生率差异无统计学意义,(P>0.05)。结论临床利用氟哌噻吨美利曲辛来治疗胃溃疡伴抑郁症患者,可有效提高胃溃疡治疗的有效率,降低抑郁量表评分,效果确切,值得推广。
Objective To observe the clinical effect of flupentixol and melitracen on patients with gastric ulcer associated with depression. Methods 100 cases of gastric ulcer with depression were randomly divided into observation group and control group, 50 cases each. The control group was given conventional drug treatment. The observation group was treated with flupentixol and melitracen on the basis of the control group. The depression self-rating scale (SDS) and gastric ulcer after treatment were recorded and compared in two groups of patients. Results The total effective rate of gastric ulcer in observation group was 96.0%, which was significantly higher than that in control group (82.0%, P <0.05). After treatment, the SDS scores of the two groups decreased to some extent compared with those before treatment, but the decrease of SDS score in the observation group was significantly greater than that of the control group (P <0.05). No abnormalities such as liver and kidney function were found in the two groups. There was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05). Conclusion Clinical use of flupentixol MTV to treat patients with gastric ulcer and depression can effectively improve the efficiency of treatment of gastric ulcer, reduce depression scale score, the effect is exact, it is worth promoting.