昆明山海棠Tripterygium hypoglaucum是雷公藤属植物,民间常用于治疗跌打骨折、关节炎、肿瘤等,具有较高的药用价值。昆明山海棠中的化学成分主要是二萜、三萜和倍半萜类生物碱,此外还有黄酮、甾体、鞣质、糖类等成分,其中二萜和生物碱是其主要活性成分。现代药理研究表明,昆明山海棠具有抗炎、抗肿瘤、免疫抑制、抗病毒等作用。临床上多用于治疗类风湿性关节炎、银屑病、慢性荨麻疹等疾病。对昆明山海棠的化学成分、药理作用和临床应用进行综述,为昆明山海棠的开发利用提供参考。 Tripterygium hypoglaucum Tripterygium hypoglaucum is Tripterygium, folk commonly used in the treatment of broken fractures, arthritis, cancer, etc., with high medicinal value. The main constituents of Kunming Begonia are diterpene, triterpenoids and sesquiterpenoids, as well as flavonoids, steroids, tannins and sugars. Among them, diterpenes and alkaloids are the main active components. Modern pharmacological studies have shown that Kunming Begonia has anti-inflammatory, anti-tumor, immunosuppression, antiviral and other effects. Clinically used for the treatment of rheumatoid arthritis, psoriasis, chronic urticaria and other diseases. The chemical constituents, pharmacological effects and clinical application of Begonia kunming were reviewed, which could provide references for the development and utilization of Begonia kunming.