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目的:探讨左氧氟沙星注射液用于治疗泌尿生殖系统感染的安全性。方法:选取2008年~2013年间于我院接受治疗的泌尿生殖系统感染患者为研究对象,根据抗生素使用情况分为氧氟沙星组73例和左氧氟沙星组169例。通过比较2组患者中治疗有效率以及不良反应发生率,评价左氧氟沙星注射液用疗泌尿生殖系统感染的安全性。结果:左氧氟沙星组有效率远高于氧氟沙星组,优势明显,有统计学意义,P<0.05。2组患者的不良反应情况主要集中在消化系统反应和皮肤反应2大类,不良反应发生率比较左氧氟沙星组略低,但差异不明显,不具备统计学意义,P>0.05。结论:左氧氟沙星在用于尿路感染、细菌性前列腺炎等泌尿生殖系统细菌感染的治疗时,药效明显,不良反应小,安全可靠。
Objective: To investigate the safety of levofloxacin injection in the treatment of genitourinary infections. Methods: A total of 73 patients with genitourinary tract infection treated in our hospital from 2008 to 2013 were divided into three groups: ofloxacin group and 169 of levofloxacin group according to the use of antibiotics. The safety of levofloxacin injection in the treatment of genitourinary infection was evaluated by comparing the effectiveness of treatment and the incidence of adverse reactions in the two groups. Results: The effective rate of levofloxacin group was much higher than that of ofloxacin group, the advantage was significant, P <0.05.2 group of patients with adverse reactions mainly concentrated in two categories of digestive system reactions and skin reactions, adverse reactions occurred Rates of levofloxacin group slightly lower, but the difference was not obvious, not statistically significant, P> 0.05. Conclusion: Levofloxacin is effective and safe in the treatment of urinary tract infections, bacterial prostatitis and other urogenital bacterial infections, with less adverse reactions and safety.