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目的:探讨非人工气道患者医院获得性肺炎(HAP)发生的危险因素。方法:收集北京丰台医院2006年10月至2008年9月确诊HAP 117例非人工气道患者作为观察组,与同期未发生HAP的117例非人工气道患者作为对照组,采用单因素和logistic多因素回归分析。结果:单因素分析显示年龄、吸烟、中枢神经系统疾病、慢性阻塞性肺疾病(COPD)/支气管扩张、心力衰竭、糖尿病、意识障碍、被动体位、误吸、制酸剂、抗菌素和外科手术12种因素差异有统计学意义(P<0.05),是HAP患病的可能危险因素。而无创呼吸机通气不增加HAP发生的危险。但是lo-gistic多因素回归分析确定年龄、COPD/支气管扩张和外科手术是非人工气道患者HAP发生的独立危险因素。结论:年龄、COPD/支气管扩张和外科手术是非人工气道患者HAP发生的危险因素。
Objective: To investigate the risk factors of nosocomial pneumonia (HAP) in non-artificial airway patients. Methods: A total of 117 non-artificial airway patients diagnosed with HAP from Fengtai Hospital in Beijing from October 2006 to September 2008 were selected as observation group and 117 non-artificial airway patients without HAP during the same period as control group. The univariate and logistic Multi-factor regression analysis. RESULTS: Univariate analysis showed that age, smoking, central nervous system disorders, COPD / bronchiectasis, heart failure, diabetes, disturbance of consciousness, passive body position, aspiration, antacids, antibiotics and surgery12 There were significant differences in the factors (P <0.05), which were the possible risk factors of HAP. Noninvasive ventilator ventilation does not increase the risk of HAP. However, lo-gistic multivariate regression analysis identified age, COPD / bronchiectasis, and surgery as independent risk factors for HAP in non-artificial airway patients. CONCLUSIONS: Age, COPD / bronchiectasis, and surgical intervention are risk factors for HAP in non-artificial airway patients.