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目的观察化癥回生丹对于不稳定型心绞痛患者颈动脉软斑块的作用及影响。方法将140例不稳定型心绞痛且颈部存有软斑块的患者随机分为观察组和对照组,每组70例。对照组给予常规不稳定心绞痛西药治疗,观察组则在对照组治疗基础上加用化癥回生丹治疗,2组均持续服用3个月。3个月后进行颈动脉彩超复查,检测2组患者颈总动脉中的血清总胆固醇(TC)、低密度脂蛋白(LDL-C)、高密度脂蛋白水平(HDL-C)和三酰甘油(TG)数值。结果观察组显效率和总有效率分别为71.43%和94.29%,均高于对照组的57.14%和78.57%(P<0.05)。观察组治疗后血清TC、LDL-C、HDL-C、TG数值均优于对照组(P<0.05)。观察组颈部血管斑块的改善程度优于对照组(P<0.05)。结论化癥回生丹对于颈动脉粥样硬化病情的发展有一定的防治作用,且具有很好的抗颈动脉粥样硬化作用。
Objective To observe the effect of Huizheng Huidan on carotid plaque in patients with unstable angina pectoris. Methods A total of 140 patients with unstable angina and soft plaque in the neck were randomly divided into observation group and control group, with 70 cases in each group. The control group was given conventional unstable angina pectoris. The observation group was treated with the treatment of hyperlipidemia on the basis of the control group. Both groups took 3 months continuously. Three months later, carotid color ultrasonography was performed to detect the levels of total cholesterol (TC), low density lipoprotein (LDL-C), high density lipoprotein (HDL-C) and triglyceride (TG) value. Results The effective rate and total effective rate in the observation group were 71.43% and 94.29%, respectively, which were higher than those in the control group (57.14% and 78.57%, P <0.05). The TC, LDL-C, HDL-C and TG in the observation group were better than those in the control group (P <0.05). The improvement of cervical vascular plaque in observation group was better than that in control group (P <0.05). Conclusions Chemoprevente remission has some preventive and therapeutic effects on the development of carotid atherosclerosis and has good anti-carotid atherosclerosis effects.