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目的探讨护理干预联合生物治疗对消化道肿瘤患者生存率和生活质量的影响。方法选取2011年3月至2012年9月间哈尔滨医科大学附属肿瘤医院收治的79例消化道恶性肿瘤术后联合生物治疗的患者,按照随机数字表法随机分为观察组(40例)和对照组(39例)。观察组患者予以护理干预,对照组患者行常规护理。比较两组患者1年、2年和3年的生存率,采用症状自评量表(SCL-90)对患者的精神卫生症状进行评价,采用胃肠生活质量量表对患者的生活质量进行评价。结果随访时间为1.5~3.2年,平均随访(2.6±0.7)年。观察组患者1年生存率与对照组比较差异无统计学意义(P>0.05),2年和3年生存率均高于对照组,差异均有统计学意义(P<0.05)。观察组患者各项症状评分均低于对照组,差异有统计学意义(P<0.05)。观察组患者各项生活质量评分高于对照组,差异有统计学意义(P<0.05)。结论护理干预联合生物治疗可明显提高患者的生存率,改善患者的生活质量,值得临床推广应用。
Objective To investigate the effect of nursing intervention combined with biotherapy on the survival rate and quality of life of patients with gastrointestinal cancer. Methods From March 2011 to September 2012, 79 patients with combined gastrointestinal malignant tumor treated by Affiliated Tumor Hospital of Harbin Medical University were randomly divided into observation group (40 cases) and control group Group (39 cases). Patients in observation group were given nursing intervention and patients in control group were given routine nursing care. The 1-year, 2-year and 3-year survival rates were compared between the two groups. Mental health symptoms were assessed using the Self-rating Symptom Scale (SCL-90), and the quality of life was assessed using the gastrointestinal quality of life scale . Results The follow-up time ranged from 1.5 to 3.2 years, with a mean follow-up of (2.6 ± 0.7) years. The 1-year survival rate in the observation group was not significantly different from that in the control group (P> 0.05). The 2-year and 3-year survival rates in the observation group were significantly higher than those in the control group (P <0.05). The symptom score of observation group was lower than that of control group, the difference was statistically significant (P <0.05). The scores of quality of life in the observation group were higher than those in the control group, the difference was statistically significant (P <0.05). Conclusion Nursing intervention combined with biotherapy can significantly improve the survival rate of patients and improve the quality of life of patients, it is worth clinical application.