论文部分内容阅读
目的:探讨胺碘酮治疗充血性心力衰竭(CHF)心房颤动伴快速心室率的临床疗效。方法:将106例各种原因所致的房颤伴快速心室率的CHF患者按入院顺序随机分为治疗组及对照组。两组抗CHF基础治疗相同,治疗组加用静脉负荷量胺碘酮150 mg后,再以1000μg/min静脉点滴维持6小时,500μg/min静滴18小时。同时口服胺碘酮0.2,3次/d,1周;再0.2,2次/d,1周以后以0.2,1次/d至观察终点,随诊为12个月。结果:治疗组53例使用胺碘酮治疗可显著增加抗心律失常有效性,改善左室射血分数,减少心力衰竭再住院率,42例患者转复为室性心律。结论:静脉及口服胺碘酮同时应用治疗充血性心力衰竭房颤是有效和安全的。
Objective: To investigate the clinical efficacy of amiodarone in the treatment of atrial fibrillation with rapid ventricular rate in patients with congestive heart failure (CHF). Methods: A total of 106 patients with atrial fibrillation and rapid ventricular rate caused by various causes were randomly divided into treatment group and control group. The same two groups of anti-CHF treatment, the treatment group with intravenous amiodarone 150 mg, and then to 1000μg / min intravenous maintenance of 6 hours, 500μg / min intravenous infusion of 18 hours. At the same time oral amiodarone 0.2,3 times / d, 1 week; 0.2,2 times / d, after 1 week to 0.2,1 times / d to observe the end point, followed up for 12 months. Results: In the treatment group, the use of amiodarone in 53 cases can significantly increase the effectiveness of anti-arrhythmia, improve left ventricular ejection fraction, reduce the re-hospitalization rate of heart failure, 42 patients converted to ventricular rhythm. Conclusions: Simultaneous intravenous and oral administration of amiodarone in the treatment of atrial fibrillation with congestive heart failure is effective and safe.