PYRROLIDINE DITHIOCARBAMATE INHIBITS NF-KB ACTIVATION AND ENHANCES TNF-INDUCED APOPTOSIS IN HUMAN BR

来源 :中国癌症研究：英文版 | 被引量 : 0次 | 上传用户：xjtcfx

【摘要】

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Objective: To determine whether pyrrolidine dithio-carbamate(PDTC) enhances TNFα-induced apoptosis in cultured breast cancer cells and explore the role of NF-

【作者】

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TUGang YAOZhen-xiang

【机构】

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DepartmentofSurgery

【出处】

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中国癌症研究：英文版

【发表日期】

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2004年2期

【关键词】

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氮戊环二硫代氨基甲酸酯抑制作用 NF-KB 活化作用转移感应细胞凋亡乳房肿瘤细胞 PDTC TNFΑ

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Objective: To determine whether pyrrolidine dithio-carbamate(PDTC) enhances TNFα-induced apoptosis in cultured breast cancer cells and explore the role of NF-κB in TNFα-induced apoptosis. Methods: Human breast cancer cell lines MCF-7 and MDA-MB-435s were

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PYRROLIDINE DITHIOCARBAMATE INHIBITS NF-KB ACTIVATION AND ENHANCES TNF-INDUCED APOPTOSIS IN HUMAN BR

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