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目的：观察和评价羊膜移植在重建眼表面手术中的应用价值。方法：采用保存人羊膜联合自体或亲属健康眼的角膜缘移植治疗眼表面疾病４８例５２只眼。结果：术后随访６０～９２周，５２只眼中，４７只眼获得稳定的眼表面（除周边部有少量纤维血管翳外，中央部无新生血管及复发性上皮缺损发生），３７只眼角膜透明或半透明，３１只眼脱盲。结论：羊膜移植不是上皮移植，而是改良基底的手术，以保存人羊膜为基底膜，自体或亲属健康眼的角膜缘为上皮细胞来源，重建眼表面治疗眼表面疾病，初步结果显示是一种有价值的方法，其作用机制尚不清楚。
Objective: To observe and evaluate the value of amniotic membrane transplantation in reconstruction of ocular surface surgeries. Methods: Forty - eight eyes (52 eyes) of ocular surface diseases were treated with corneal limbal transplantation of preserved human amnion combined with autologous or relative healthy eyes. Results: After 60-92 weeks of follow-up, 47 eyes of 52 eyes achieved stable ocular surface (no neovascularization and recurrent epithelial defect occurred in the central part except for a few fibrovascular vessels in the peripheral part), 37 corneas Transparent or translucent, 31 eyes were blind. CONCLUSIONS: Amniotic membrane transplantation is not an epithelial transplantation but an operation to improve the basement to preserve the human amniotic membrane as the basement membrane. The corneal limbal origin of autologous or relative healthy eyes is the source of epithelial cells. Reconstruction of the ocular surface for the treatment of ocular surface diseases shows preliminary results as a Valuable method, the mechanism of action is not clear.