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目的探讨参麦注射液对冠心病患者高敏肌钙蛋白及游离脂肪酸水平的影响。方法回顾性分析2012年9月至2014年12月冠心病110例患者的临床资料,其中55例接受常规治疗为对照组,另55例给予参麦注射液与常规治疗为观察组,比较治疗前后两组患者总胆固醇(TC)、三酰甘油(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)及高敏肌钙蛋白、游离脂肪酸水平的变化。结果治疗后,两组血脂指标TC、TG、HDL-C、LDL-C水平差异未见统计学意义(P>0.05),但观察组高敏肌钙蛋白、游离脂肪酸水平低于对照组,差异有统计学意义(P<0.05)。结论参麦注射液能显著降低冠心病患者的高敏肌钙蛋白、游离脂肪酸水平,可有效保护心肌功能。
Objective To investigate the effect of Shenmai injection on high-sensitivity troponin and free fatty acid in patients with coronary heart disease. Methods The clinical data of 110 patients with coronary heart disease from September 2012 to December 2014 were retrospectively analyzed. Among them, 55 patients received routine treatment as control group, another 55 patients received Shenmai injection and conventional therapy as observation group, The changes of total cholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C), high-sensitivity troponin and free fatty acid in two groups were compared. Results After treatment, the levels of TC, TG, HDL-C and LDL-C in the two groups showed no significant difference (P> 0.05), but the levels of high-sensitivity troponin and free fatty acid in the observation group were lower than those in the control group Statistical significance (P <0.05). Conclusion Shenmai injection can significantly reduce high-sensitive troponin, free fatty acid levels in patients with coronary heart disease, which can effectively protect myocardial function.