非酒精性脂肪性肝病(non-alcoholic fatty liver disease,NAFLD)是一种无过量饮酒史,以肝实质细胞脂肪变性和脂肪贮积为特征的临床病理综合征~([1])。绝大多数脂肪肝患者无任何症状,多在体检或影像学检查中发现存在脂肪肝。随着国人生活水平的提高,近年来,我国脂肪肝发病率呈逐年上升趋势~([2])。脂肪性肝病正严重威胁人们的健康,已经成为仅次于病毒性肝炎的第二大肝病,被认为是引起隐蔽 Non-alcoholic fatty liver disease (NAFLD) is a clinical pathological syndrome characterized by an absence of excessive alcohol consumption, characterized by hepatic steatosis and adipose accumulation [1]. Most patients with fatty liver without any symptoms, and more in physical examination or imaging examination found that there is fatty liver. With the improvement of people’s living standards in recent years, the incidence of fatty liver in China showed an upward trend year by year (2). Fatty liver disease is a serious threat to people’s health, has become the second largest liver disease after viral hepatitis, is considered to cause hidden