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目的探讨中性粒细胞分叶过多在孕妇贫血中的重要意义。方法研究分三组,研究一组缺铁性贫血伴有中性粒细胞分叶过多的孕妇62例,研究二组缺铁性贫血不伴有中性粒细胞分叶过多的孕妇68例,对照组为健康的孕妇70例。血常规检查的同时制作血涂片观察粒细胞形态,计数5叶核及6叶核以上中性粒细胞的百分比;化学发光法检测血清蛋白铁、维生素B12和叶酸。结果研究一组血清叶酸和维生素B12的含量明显低于对照组和研究二组(P<0.01);研究一组的有效率明显低于研究二组(92.0%vs 58.0%,P<0.01)。结论建议临床对缺铁性贫血孕妇常规观察粒细胞形态,用于鉴别是单纯性缺铁性贫血还是混合型贫血,这对于指导贫血孕妇这一特殊群体的治疗有重要意义。
Objective To investigate the significance of neutrophil lobulation in pregnant women with anemia. Methods Study divided into three groups, study of a group of iron deficiency anemia associated with excessive neutrophil granulomatous pregnant women 62 cases of iron deficiency anemia in two groups without neutrophil follicles in 68 pregnant women , The control group of healthy pregnant women 70 cases. Blood smears at the same time making blood smears observed granulocyte morphology, counting 5 leaf nuclei and 6 leukocytes above the percentage of neutrophils; chemiluminescence method for detecting serum protein iron, vitamin B12 and folic acid. Results The levels of serum folate and vitamin B12 in the study group were significantly lower than those in the control group and the study two group (P <0.01). The effective rate in the study group was significantly lower than that in the study two group (92.0% vs 58.0%, P <0.01). Conclusion It is suggested that clinical observation of granulocyte morphology in pregnant women with iron deficiency anemia should be used to distinguish between simple iron deficiency anemia and mixed anemia, which is of great significance for the treatment of this special group of pregnant women with anemia.