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目的观察山莨菪碱治疗人流综合征的疗效。方法对妊娠１２周内要求人流手术的孕妇常规用６５４－２作麻醉或镇痛药物共２０００例，作为用药组。随机选３００例不用任何麻醉药或镇痛药孕妇作对照组。孕妇取膀胱截石位，常规消毒后用６～７号针刺入宫颈０．５～１ｃｍ处，回抽无血后注入６５４－２，２．５～５ｍｇ，１～２ｍｉｎ后进行手术。结果用药组疗效明显优于对照组，有显著差异性（Ｐ＜０．０１）。用药组无１例发生人流综合征，极少数出现呕吐（１％）、恶心（４％）、出汗（０．８％）现象，而对照组发生人流综合征为 １２％。结论 ６５４－２在人流术中应用，不仅预防人流综合征效果良好，且有明显的镇痛，松驰子宫颈和促使宫缩的功能。人流中应用６５４－２简便、安全、效果好，值得临床推广作用。
Objective To observe the effect of anisodamine in treating flow syndrome. Methods Pregnant women who requested abortion within 12 weeks of pregnancy routinely used 654-2 as anesthetic or analgesic drugs for a total of 2000 cases as the medication group. Randomly selected 300 cases without any anesthetic or analgesic pregnant women as a control group. Pregnant women to take bladder lithotomy position, routine disinfection with 6 ~ 7 acupuncture into the cervix 0.5 ~ 1cm Department, no blood pumping back into the 654-2, 2.5 ~ 5mg, 1 ~ 2min after surgery. The results of the treatment group was significantly better than the control group, there was significant difference (P <0.01). None of the patients in the medication group developed flow syndrome, with very few cases of vomiting (1%), nausea (4%) and sweating (0.8%), compared with 12% of controls. Conclusion 654-2 in abortion, not only to prevent the flow of people syndrome, good effect, and obvious analgesia, relaxation of the cervix and promote uterine contractions. Flow of people in the application of 654-2 simple, safe, effective, worthy of clinical promotion.