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目的:探讨新生儿缺氧缺血性脑病(H IE)与血钙、血钠及血小板计数变化的关系。方法:统计分析56例H IE患儿血钙、血钠及血小板计数的变化,比较H IE患儿与非H IE患儿、不同程度H IE患儿、足月H IE患儿与早产H IE患儿之间血钙、血钠及血小板计数的变化情况。结果:H IE患儿较非H IE患儿其血钙、血钠及血小板计数明显下降,差异有统计学意义(P<0.01),且下降程度与H IE病情严重度成正相关。早产H IE患儿较足月H IE患儿其血钙、血小板数降低更明显(P<0.01),两者血钠差异无统计学意义(P>0.05)。结论:新生儿H IE时可出现血钙、血钠降低及血小板计数减少,早产儿血钙、血小板计数下降更明显,下降程度与病情严重度成正相关,在医疗设备条件有限的基层医院监测血钙、血钠及血小板计数对判断病情、防止病情的加重有很大帮助。
Objective: To investigate the relationship between neonatal hypoxic-ischemic encephalopathy (H IE) and changes of serum calcium, serum sodium and platelet count. Methods: The changes of serum calcium, serum sodium and platelet count in 56 HIE children were statistically analyzed. H children with H IE, H children with different degrees of HIE, Children between calcium, sodium and platelet count changes. Results: The serum calcium, serum sodium and platelet counts of children with H IE were significantly lower than those without H IE (P <0.01), and the degree of decline was positively correlated with the severity of H EIE. The serum calcium and platelet count of HIE patients with preterm labor were more obvious than those of full-time H IE patients (P <0.01). There was no significant difference in serum sodium between the two groups (P> 0.05). Conclusions: Serum calcium, hyponatremia and decrease of platelet count may occur in neonatal H IE. The decrease of serum calcium and platelet count in premature infants is more obvious. The degree of decrease is positively correlated with the severity of illness. Monitoring blood in the primary hospital with limited medical equipment Calcium, serum sodium and platelet count to determine the condition, to prevent the aggravating condition is of great help.