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目的 :观察前列腺素E1治疗糖尿病性脑梗死的疗效。方法 :前列腺素E1组给予生理盐水 2 5 0ml加入前列腺素E110 0 μg,静脉滴注 ,每日一次 ,15d一疗程 ,复方丹参组加入复方丹参 16ml ,静脉滴注 ,疗程同前。结果 :前列腺素E1组总有效率94 .2 3% ,复方丹参组 86 .96 % ,两组比较有显著性差异 (P <0 .0 5 )。全血粘度、血浆粘度、红细胞刚性指数、红细胞聚集指数纤维蛋白原治疗后与复方丹参组比较明显改善 (P <0 .0 5 )。结论 :前列腺素E1治疗糖尿病性脑梗死在临床疗效及改善血液流变学指标方面均优于复方丹参
Objective: To observe the efficacy of prostaglandin E1 in the treatment of diabetic cerebral infarction. Methods: The prostaglandin E1 group was given physiological saline 250ml added prostaglandin E110 0, intravenous drip, once daily, 15d a course of treatment, compound Salvia group added compound Danshen 16ml, intravenous infusion, the same treatment. Results: The total effective rate of prostaglandin E1 group was 94.23% and that of compound Danshen group was 86.96%. There was a significant difference between the two groups (P <0.05). Whole blood viscosity, plasma viscosity, erythrocyte rigidity index, erythrocyte aggregation index fibrinogen were significantly improved compared with compound Danshen group (P <0.05). Conclusion: Prostaglandin E1 is superior to compound Salvia miltiorrhiza Bge in the treatment of diabetic cerebral infarction and the improvement of hemorheology indexes