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作者试图用含PEG的催化体系催化雌甾的亲核取代.采用PEG-400/KOH/CH_3OH体系,代替作者曾设计和应用过的冠醚/亚铜盐/CH_3ONa体系,进行2-及4-溴雌二
The authors attempted to catalyze the nucleophilic substitution of estrone using a PEG-containing catalytic system.Using the PEG-400 / KOH / CH_3OH system instead of the crown ether / cuprous salt / CH_3ONa system which the author designed and applied, 2- and 4- Bromo-estrus