研究表明动脉粥样硬化是一种慢性免疫炎症性疾病。目前与T淋巴细胞相关的免疫细胞及免疫分子在冠心病发生发展中的作用已成为研究热点,近年来在急性冠状动脉综合征患者动脉粥样斑块和外周血中发现了一种不同寻常的T细胞——CD4+CD28-T细胞,并发现CD4+CD28-T淋巴细胞在急性冠状动脉综合征中可持续存在,且与预后有关,同时可能成为急性冠状动脉综合征治疗的新的靶点。 Research shows that atherosclerosis is a chronic immunological inflammatory disease. Currently, the role of immune cells and immune molecules related to T lymphocytes in the development of coronary heart disease has become a research hotspot. In recent years, an unusual pattern of atherosclerotic plaque and peripheral blood has been found in patients with acute coronary syndrome T cells - CD4 + CD28-T cells, and found that CD4 + CD28-T lymphocytes in acute coronary syndromes persist, and with the prognosis, and may be a new target for the treatment of acute coronary syndrome .