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目的分析71万例新生儿先天性甲状腺功能减退症(CH)筛查及治疗情况。方法调查2001年7月-2012年12月在聊城地区参加新生儿疾病筛查的新生儿,所有筛查对象均在出生72h并充分哺乳6次以上后采集足跟血滴在专用滤纸上,递送至新生儿疾病筛查中心统一检验TSH含量。结果筛查的71万例新生儿中,阳性患儿2066例,阳性率0.29%,确诊CH394例,发病率1/1821,确诊患儿给予免费治疗至6周岁。结论聊城地区CH发病率在全国处于较高水平;新生儿疾病筛查是预防残疾儿发生、提高人口素质的有效预防措施之一。
Objective To analyze the screening and treatment of 710,000 neonates with congenital hypothyroidism (CH). Methods To investigate the newborns who participated in neonatal screening in Liaocheng from July 2001 to December 2012. All the samples were collected 72h after birth and fully breastfeeding for more than 6 times. To the neonatal screening centers uniform testing TSH content. Results Among the 710,000 newborns screened, 2066 were positive, with a positive rate of 0.29%. The number of confirmed CH394 cases was 1/1821, and the diagnosed children were given free treatment to 6 years of age. Conclusion The incidence of CH in Liaocheng is at a high level in the country. Neonatal screening is one of the effective preventive measures to prevent the occurrence of disabled children and improve their quality.