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目的了解当前该病的研究状况,为广大专业人员深入开展非小细胞肺癌的研究提供参考信息。方法下载Pubmed数据库中2008-2009这2年发表的非小细胞肺癌研究文献的主题词,统计主题词出现的频次,截取频次大于198次的主题词作为高频主题词。两两统计高频主题词在同一篇文献中出现的频率,形成主题词共现矩阵,利用spss统计软件对矩阵做聚类分析,得到该主题研究热点。结果共检出2年非小细胞肺癌文献3 078篇,出现频次超过198次的主题词43个,通过对这43个高频主题词聚类得到5个研究热点。结论目前国外对非小细胞肺癌的研究热点主要集中在放疗、外科手术及化疗、诊断、病因学研究、抗肿瘤用药的研发及应用等方面。
Objective To understand current research status of the disease and provide reference information for the majority of professionals to conduct in-depth research on non-small cell lung cancer. Methods Download the topic words of the non-small cell lung cancer research literature published in the Pubmed database for the two years from 2008 to 2009. Count the frequency of the occurrence of the topic words and cut the subject words whose frequency is greater than 198 times as high frequency keywords. Twenty-two statistics of the frequency of high-frequency topic words appearing in the same document form the co-occurrence matrix of the topic words. The cluster analysis of the matrix is performed using spss statistical software to obtain hot topics of the topic. Results A total of 3,078 non-small cell lung cancer (NSCLC) cases were detected for 2 years. There were 43 subject terms with more than 198 frequency occurrences. Through the clustering of these 43 high frequency topic words, five research hotspots were obtained. Conclusion At present, the research hotspots of non-small cell lung cancer in foreign countries mainly focus on radiotherapy, surgery and chemotherapy, diagnosis, etiology research, development and application of anti-tumor drugs.