静脉滴注青霉素葡萄糖溶液治疗严重感染。临床使用日益广泛,但有关青霉素在10%葡萄糖溶液中的稳定性,尚少研究报道。一般认为混合后立即使用是可以的(4小时用完)。但葡萄糖注射液的pH,药典规定为3.2～5.5,药剂学和制剂手册则规定pH3.8～4.0最稳定。武汉地区夏季严热,室温高达37℃。因之,在此室温下研究青霉素的稳定性以供临床使用参考。 Intravenous injection of penicillin glucose solution for severe infections. The clinical use of more and more widely, but the stability of penicillin in 10% glucose solution, little research has been reported. It is generally thought that it is okay to use it immediately after mixing (4 hours run out). However, the pH of glucose injection, Pharmacopoeia is 3.2 ~ 5.5, Pharmacy and Preparation Manual provides the most stable pH 3.8 ~ 4.0. Wuhan summer hot, room temperature up to 37 ℃. Therefore, the stability of penicillin at room temperature for clinical use for reference.