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淋巴结转移是宫颈癌肿瘤细胞转移的最早特征,宫颈癌患者局部淋巴结状况直接影响患者的预后并决定着辅助治疗方案的制定。然而对患者盆腔所有淋巴结进行评估是一件十分繁杂的事情,前哨淋巴结(SLN)能反映整个盆腔淋巴结的转移状况,其研究使大多数早期宫颈癌患者避免不必要的盆腔淋巴结清扫术。目前常用的淋巴结识别方法有染料法、放射性核素示踪法及联合法。淋巴结微转移检测法(如:免疫组化法、连续切片法、鳞状细胞癌抗原检测及淋巴结HPV检测法等)能提高SLN的诊断准确性。
Lymph node metastasis is the earliest feature of cervical cancer cell metastasis. The local lymph node status of cervical cancer patients directly affects the prognosis of patients and determines the development of adjuvant therapy. However, evaluating all pelvic lymph nodes in patients is a very complicated task. SLN can reflect the metastatic status of pelvic lymph nodes. The study of most patients with early stage cervical cancer avoided unnecessary pelvic lymph node dissection. Currently used lymph node identification methods dye method, radionuclide tracer method and the joint law. Lymph node micrometastases (such as immunohistochemistry, serial sections, squamous cell carcinoma antigen test and lymph node HPV test, etc.) can improve the diagnostic accuracy of SLN.