论文部分内容阅读
We present a 15-month-old boy who developed fulminant hepatic failure after ingesting 10 ml of clove oil. After 24 h, the ALT level was in excess of 13,000 U/l, with blood urea and creatinine of 11.8 mmol and 134 μmol/l respectively. T he hepatic impairment resolved after intravenous administration of N-acetylcyst eine so that 6 h later, the ALT level was approximately 10,000 U/l. His liver sy nthetic function and clinical status improved over the next 4 days. This is the first such case report of its kind in Europe. Analysis of a national database re vealed a 14-fold increase in home accidents related to aromatherapy from 1994-1999. Clove oil has important hepatotoxic effects. Conclusion:Recent growth in a romatherapy sales has been accompanied by an unfortunate increase in accidental poisoning from these products. Clove oil warrants special attention. Ingesting a s little as 10 ml causes hepatotoxicity which can be treated with N-acetylcyste ine.
We present a 15-month-old boy who developed fulminant hepatic failure after ingesting 10 ml of clove oil. After 24 h, the ALT level was in excess of 13,000 U / l, with blood urea and creatinine of 11.8 mmol and 134 μmol / l respectively. T he hepatic impairment resolved after intravenous administration of N-acetylcyte eine so that 6 h later, the ALT level was approximately 10,000 U / l. His liver sy nthetic function and clinical status improved over the next 4 days. This is the first such case report of its kind in Europe. Analysis of a national database re vealed a 14-fold increase in home accidents related to aromatherapy from 1994-1999. Clove oil has important hepatotoxic effects. Conclusion: Recent growth in a romatherapy sales has been accompanied by an unfortunate increase in accidental poisoning from these products. Clove oil warrants special attention. Ingesting as little as 10 ml causes hepatotoxicity which can be treated with N-acetylcysteine.