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目的：研究静脉包被支架在动脉内置入后的病理生理过程。方法：全麻后在Ｘ 线透视下，５ 只杂种狗的两侧髂动脉内分别置入静脉包被的和非包被的ＰＳ 支架。术后１ 、２ 及３ 个月时分别处死，取支架段血管进行组织化学染色，透视和扫描电镜检查。结果：静脉包被支架内皮化速度（１ 个月时完成） 明显快于非静脉包被支架（３ 个月时完成） 。静脉包被支架内炎性反应突出，表现为大量淋巴细胞浸润和少量成纤维细胞浸润，于２ 个月时基本消失。静脉包被支架未见支架内血栓形成。动脉内弹力层断裂见于所有支架部位，但是静脉包被较轻。动脉与包被的静脉之间的间隙在１ 个月内完全消失。结论：动静脉之间的相融性良好。自制静脉包被支架安全可靠，内皮化速度快对再狭窄有一定的积极作用
Objective: To study the pathophysiological process of intravenous stent implantation in artery. Methods: Under general anesthesia, vein-coated and non-coated PS scaffolds were implanted into iliac artery on both sides of 5 hybrid dogs under X-ray fluoroscopy. At 1, 2 and 3 months after operation, all the animals were sacrificed and the vessels of the stent were stained by histochemical staining, fluoroscopy and scanning electron microscopy. Results: The rate of endothelialization of the vein-coated stent (completed at 1 month) was significantly faster than that of the non-vein-coated stent (completed at 3 months). Intravenous stent stent prominent inflammatory response, manifested as a large number of lymphocytic infiltration and a small amount of fibroblast infiltration, basically disappeared at 2 months. No stent thrombosis was found in the vein-covered stent. Endarterectomy is seen in all stent sites, but the veins are coated less. The gap between the artery and the coated vein completely disappeared within 1 month. Conclusion: The arterial and venous compatibility is good. Self-made stent-graft safe and reliable, rapid endothelialization has some positive effects on restenosis