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目的观察泽芪汤治疗肝硬化顽固性腹水的临床疗效,探索顽固性腹水治疗的办法。方法将86例患者随机分为治疗组56例和对照组30例。对照组给予保肝利尿、输注人血白蛋白等治疗;治疗组在对照组基础上加用泽芪汤治疗。比较2组顽固性腹水消退治疗效果,治疗后血清谷丙转氨酶(ALT)、白蛋白(ALB)、胆红素(TBil)、醛固酮(ALD)的水平。结果泽芪汤治疗组较对照组治疗顽固性腹水有更好的临床疗效,2者比较有显著性差异(P<0.05)。治疗后2组间各项生化指标比较均有显著性差异(P均<0.05)。结论泽芪汤能有效促进顽固性腹水的消退,改善患者肝功能,降低醛固酮水平。
Objective To observe the clinical efficacy of Ze Qi Tang in the treatment of refractory ascites due to liver cirrhosis and to explore the treatment of refractory ascites. Methods 86 patients were randomly divided into treatment group 56 cases and control group 30 cases. The control group was given liver protection diuretic, infusion of human serum albumin and other treatment; treatment group in the control group based on the use of Ze Qi Tang treatment. The therapeutic effect of refractory ascites and the levels of serum ALT, ALB, TBil and ALD were compared between the two groups. Results Ze Qitang treatment group than the control group of refractory ascites have a better clinical efficacy, the two were significantly different (P <0.05). After treatment, the biochemical indexes between the two groups were significantly different (all P <0.05). Conclusion Ze Qitang can effectively promote the regression of refractory ascites, improve liver function and reduce aldosterone levels.