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作者以日本厚生省研究班中山健太郎等的研究为中心,对乳儿维生素 K 缺乏症的现状作如下概述:一、小儿维生素 K 缺乏症的分类1.新生儿出血性疾病(新生儿黑粪症):极小部分是因肝机能未成熟为基础,凝血因子合成障碍,大部分是因维生素 K 缺乏,凝血因子(Ⅱ,Ⅶ,Ⅸ,Ⅹ)活性低下。新生儿黑粪症在生后1～3天达高峰,通常发生在生后1周以内。2.出生1周以后发生的维生素 K 缺乏症称为乳儿维生素 K 缺乏症。在先天性胆道闭锁等引起的脂溶
The author of the Japanese Ministry of Health Research Institute Kentaro Zhongshan Kentaro as the center, the status of vitamin K deficiency in infants are summarized as follows: First, the classification of children with vitamin K deficiency 1 neonatal hemorrhagic disease (neonatal black faecal disease): A very small part is due to immature liver function, clotting factor synthesis disorders, mostly due to vitamin K deficiency, coagulation factors (Ⅱ, Ⅶ, Ⅸ, Ⅹ) activity is low. Neonatal black fecal disease peak 1 to 3 days after birth, usually occurs within 1 week after birth. 2. One week after birth, vitamin K deficiency is called vitamin K deficiency in infants. In congenital biliary atresia caused by fat-soluble