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目的 :比较茵陈蒿汤乙醇提取物与水提取物对CCl4导致的肝损伤小鼠的保肝效果。方法 :以CCL4造小鼠肝损伤模型 ,用比色法检测两者对肝体比、总胆固醇 (CH)、谷丙转氨酶 (GPT)、甘油三酯 (TG)和丙二醛 (MDA)等指标的抑制作用。结果 :茵陈蒿汤乙醇提取物对以上诸指标的抑制作用明显优于水提取物 (P <0 .0 5 ) ,并呈剂量依赖。结论 :茵陈蒿汤乙醇提取物的抗肝损伤效果优于水提取物
Objective : To compare the liver protection effect of ethanol extract and water extract of Yinchenhao decoction on CCl4-induced liver injury in mice. METHODS: The liver injury model of mice was established with CCL4, and the liver to body ratio, total cholesterol (CH), alanine aminotransferase (GPT), triglyceride (TG) and malondialdehyde (MDA) were measured by colorimetry. Inhibition of indicators. RESULTS: The ethanol extract of Yinchenhao Decoction had significantly better inhibitory effects than the water extract (P < 0.05) in a dose-dependent manner. Conclusion :Ethanol extract of Yinchenhao decoction is better than water extract