感染流感病毒是导致流感甚至死亡的一个主要原因 ,尤其对于年幼儿童、老年人、免疫减弱个体及慢性心血管疾病、呼吸性疾病或糖尿病的患者。由于流感病毒的高突变性而使防止或治疗流感 A,B型的抗病毒药物和疫苗的研究受到很大阻碍。 1 999年 ,两种抗流感病毒神经氨酸酶抑制剂扎 Influenza virus infection is a leading cause of flu and even death, especially in young children, the elderly, immunocompromised individuals and patients with chronic cardiovascular disease, respiratory disease, or diabetes. Studies on the prevention or treatment of influenza A, B antivirals and vaccines have been hampered by the high mutationality of the influenza virus. In 1999, two anti-influenza virus neuraminidase inhibitors were ligated