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目的:探讨早发型重度子痫前期的围产结局。方法:回顾性分析249例重度子痫前期患者的临床资料,妊娠<34周102例分为早发型重度子痫前期组(早发型组)和妊娠≥34周147例为晚发型重度子痫前期组(晚发型组),评价孕妇围产结局和国产儿结局。结果:早发型组孕妇器官受累高达52.9%,围产儿死亡率11.8%,明显高于晚发型组,差异有统计学意义(P<0.05);早发型组分娩孕周为(33.1±2.8)周,早于晚发型组(38.2±1.6)周,差异有统计学意义(P<0.05)。结论:早发型重度子痫前期孕妇的病情重,异常围产儿结局发生率高、存活率低,适当期限内的保守治疗有助于改善母儿结局。
Objective: To investigate the perinatal outcome of early-onset severe preeclampsia. Methods: A retrospective analysis of 249 patients with severe preeclampsia clinical data, 102 cases of pregnancy <34 weeks were divided into early-onset severe preeclampsia group (early-onset group) and 147 weeks of pregnancy 147 cases of late onset severe preeclampsia Group (late-onset group), evaluate the perinatal outcome of pregnant women and domestic children’s outcome. Results: Early pregnant women had 52.9% of pregnant women’s organs and perinatal mortality rate was 11.8%, which was significantly higher than that of the late-onset group (P <0.05). The gestational weeks of the early-onset group was (33.1 ± 2.8) weeks , Earlier than the late-onset group (38.2 ± 1.6) weeks, the difference was statistically significant (P <0.05). CONCLUSION: Premature onset severe preeclampsia is characterized by severe illness, abnormal perinatal outcome and low survival rate. Conservative treatment within the appropriate time may help to improve the maternal and infant outcomes.