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白花丹酸是从植物白花丹(Plumbago Zey-lanica Linn.)中分离得到的天然产物,化学结构为β—(2,3—二羟基苯甲酰基)丁酸(1),其手性碳原子的立体化学问题未经考查。药理实验表明,它具有镇咳,祛痰和抑菌等作用。 1986年,王德心等曾以邻苯二酚及邻苯二甲醚为原料,试图用Friedel-Crafts反应,合成
Plumbagin is a natural product isolated from Plumbago Zey-lanica Linn. The chemical structure is 1- (2,3-dihydroxybenzoyl) butanoic acid (1), the chiral carbon atom Three-dimensional chemical problems without examination. Pharmacological experiments show that it has antitussive, expectorant and antibacterial effects. In 1986, Wang Dexin had catechol and phthalate as a raw material, trying Friedel-Crafts reaction, synthesis