胆汁酸是胆固醇的主要代谢产物,在消化吸收中起着极重要的作用。胆汁酸也是胆固醇通过胆汁排泌的一种形式。胆汁酸代谢包括合成,排泌及肠肝循环,需经过肝脏、胆道,门脉系统及肠道等一个广泛途径,因此许多消化系统疾病可引起胆汁酸的代谢紊乱。反之,胆汁酸的代谢紊乱必将导致消化系统许多疾病。 Bile acid is the main metabolite of cholesterol, plays an important role in digestion and absorption. Bile acids are also a form of cholesterol excreted through the bile. Bile acid metabolism, including synthesis, excretion and enterohepatic circulation, need to go through a wide range of pathways such as the liver, biliary tract, portal system and intestine, and therefore many digestive diseases can cause metabolic disorders of bile acids. Conversely, the metabolic disorder of bile acids will lead to many diseases of the digestive system.