鼠管状线虫(Sypbacia muris)是一种寄生于大鼠盲肠、结肠的常见普通线虫,偶可感染小鼠。尽管被感染的动物通常无明显的症状,但可影响动物的生长发育,干扰实验结果。据报道在诱发大鼠关节炎试验中,感染的大鼠所产生的损伤程度较对照组轻,提示感染大鼠对抗原的免疫应答能力较低;也有报道在重度感染时动物体重减轻。 Sypbacia muris is a common, common nematode parasitic to the cecum and colon of rats that can infect mice. Although the infected animals usually have no obvious symptoms, they can affect the growth and development of the animals and interfere with the experimental results. It has been reported that in rats induced by arthritis, the degree of damage in infected rats is lower than that in control mice, suggesting that the infected rats have a lower ability to respond to antigens; and that animals are also reported to lose weight in severe infections.