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目的研究时辰放疗和常规放疗治疗鼻咽癌的疗效及毒副反应。方法65例初治鼻咽癌患者随机分为常规放疗组和时辰放疗组,分别为31例和34例。两组均采用相同放射治疗方法和治疗剂量。常规放疗组治疗时间是在上午8∶00~10∶00时进行,而时辰放疗组治疗是在20∶00~22∶00时进行。结果放疗结束个月时,时辰放疗组的鼻咽部及颈部的肿瘤完全消退率均比常规放疗组高(P<0.05)。时辰治疗组的副作用比常规治疗组低。结论时辰放疗可提高鼻咽癌的疗效,并且能够降低放疗的副作用。
Objective To study the curative effect and toxicity of hourly radiotherapy and conventional radiotherapy for nasopharyngeal carcinoma. Methods Sixty-five patients with newly diagnosed nasopharyngeal carcinoma were randomly divided into routine radiotherapy group and hourly radiotherapy group, with 31 cases and 34 cases respectively. Both groups used the same radiation treatment and dose. Conventional radiotherapy group treatment time is in the morning 8:00 ~ 10:00 when the time radiotherapy group treatment is carried out at 20:00 ~ 22:00. Results At the end of radiotherapy, the complete remission rate of nasopharynx and neck in the time-radiotherapy group was higher than that in the conventional radiotherapy group (P <0.05). The adverse effects of the treatment group were lower than those of the conventional treatment group. Conclusion Time-radiotherapy can improve the efficacy of nasopharyngeal carcinoma, and can reduce the side effects of radiotherapy.