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目的研究盐酸阿比朵尔片(抗感冒药)治疗流行性感冒的疗效和安全性。方法用多中心随机双盲平行对照试验设计,随机分为试验组(108例)与对照组(105例),2组分别口服盐酸阿比朵尔片或利巴韦林片每次0.2g,疗程共6天。结果2组临床总效率(91.67%vs82.86%)和痊愈率(82.41%vs73.33%)比较均无显著性差异(PP分析,P>0.05);症状总改善率中位数均达100%。2组药物不良反应发生率(7.62%vs5.71%)比较无显著性差(P>0.05)。结论在流感发病早期,用盐酸阿比朵尔片可缩短疾病持续时间,减轻症状,且耐受性较好。
Objective To study the efficacy and safety of abidol hydrochloride tablets (anti-cold medicine) in the treatment of influenza. Methods A multicenter randomized, double-blind, parallel-controlled trial was designed and randomly divided into experimental group (n = 108) and control group (n = 105). The two groups were treated with 0.2 g of abidol hydrochloride tablets or ribavirin tablets each time. A total of 6 days treatment. Results There was no significant difference in the total clinical efficacy (91.67% vs 82.86%) and the cure rate (82.41% vs 73.33%) in the two groups (PP analysis, P> 0.05) %. Two groups of adverse drug reactions (7.62% vs5.71%) was no significant difference (P> 0.05). Conclusion In the early stage of flu, using abiraterone hydrochloride can shorten the duration of the disease, relieve the symptoms and is well tolerated.